Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210692 | 0.91 | GAA (0.58) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL12758272 | 0.86 | NPC1 (0.57) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL21625694 | 0.85 | TOP1 (0.52) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL10242069 | 0.83 | KMT2A (0.71) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL22305399 | 0.82 | KCNK3 (0.83) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL28622654 | 0.82 | RAB9A (0.93) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL22173521 | 0.81 | THRB (0.73) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL3274053 | 0.81 | THRB (0.79) | KMT2AMEN1FKBP5NPC1RAB9A | |
| SCHEMBL7295360 | 0.81 | NR1H4 (0.60) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL27550517 | 0.80 | KMT2A (0.70) | KMT2AMEN1FKBP5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843521-A | Compound serving as thyroid hormone beta receptor agonist as well as preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |
| US-20200316032-A1 | COMPOUNDS AND COMPOSITIONS FOR INHIBITING RETINAL PIGMENT EPITHELIUM DEGENERATION AND METHODS USING THE SAME | THE SCHEPENS EYE RESEARCH, INSTITUTE, INC. | 2020-10-08 | — | — | US | disclosed |
| US-4013618-A | NITROGEN-CONTAINING STABILIZER | TOYOBO CO., LTD. (JA) | 1977-03-22 | — | — | US | disclosed |
| US-3957905-A | HALOGENATED BISPHENYL COMPOUND, ANTIMONY COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200316032-A1 | COMPOUNDS AND COMPOSITIONS FOR INHIBITING RETINAL PIGMENT EPITHELIUM DEGENERATION AND METHODS USING THE SAME | ALDH1A2, RBP4, RBP1 | KMT2A 4554/4885MEN1 4710/4885FKBP5 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.