Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.59 |
| ▸ | NOS3 | P29474 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336603 | 0.80 | MAPT (0.83) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL18806562 | 0.80 | MAPT (0.83) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL29042753 | 0.80 | MAPT (0.83) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL50646 | 0.79 | MAPT (0.68) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL7787732 | 0.78 | TSHR (0.60) | MAPTNPC1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL7048445 | 0.78 | MAPT (0.63) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL10223094 | 0.78 | NOS3 (0.61) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL11706363 | 0.76 | NOS1 (0.59) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL15435836 | 0.76 | NOS1 (0.72) | NOS1NOS3MAPTRAB9ANPC1 | |
| SCHEMBL14524471 | 0.74 | MAPT (0.67) | NOS1NOS3MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011208-A | 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES | SANDOZ LTD. (CH) | 1977-03-08 | — | — | US | claimed |
| US-4011208-A | 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES | SANDOZ LTD. (CH) | 1977-03-08 | — | — | US | disclosed |