SCHEMBL7787732

SCHEMBL7787732

[N]=Nc1ccc(C(=O)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.60
TP53 P04637 1/20 0.60
TRPA1 O75762 1/20 0.58
CA2 P00918 5/20 0.56
CA1 P00915 4/20 0.56
CA12 O43570 2/20 0.56
CA9 Q16790 2/20 0.56
SRD5A2 P31213 2/20 0.52
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
KMT2A Q03164 3/20 0.48
POLB P06746 2/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL5014892 0.81 TSHR (0.92) TSHRTP53CA2CA1CA12
Terephthalic Acid SCHEMBL27952137 0.81 TSHR (0.92) TSHRTP53CA2CA1CA12
SCHEMBL70162 0.79 TRPA1 (0.86) TSHRTP53TRPA1CA2CA1
SCHEMBL31702246 0.79 TRPA1 (0.86) TSHRTP53TRPA1CA2CA1
SCHEMBL3364649 0.79 TRPA1 (0.86) TSHRTP53TRPA1CA2CA1
SCHEMBL9865481 0.79 TSHR (0.67) TSHRTP53TRPA1CA2CA1
SCHEMBL70163 0.79 TRPA1 (0.86) TSHRTP53TRPA1CA2CA1
SCHEMBL11706353 0.78 NOS1 (0.59) KMT2ANPC1ALDH1A1SMN1; SMN2MAPT
Terephthalic Acid SCHEMBL25175830 0.78 TSHR (0.86) TSHRTP53CA2CA1CA12
Terephthalic Acid SCHEMBL175823 0.78 TSHR (1.00) TSHRTP53CA2CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696619-B1 Process for dyeing of paper CIBA SC HOLDING AG (CH) 2001-11-14 EP claimed
EP-0696619-B1 Process for dyeing of paper CIBA SC HOLDING AG (CH) 2001-11-14 EP disclosed
EP-0681004-B1 Double acid azo dyes having a hydroxypyridone-type coupler as well as their intermediate products BASF AG (DE) 1997-07-02 EP disclosed
US-5621107-A USED AS COUPLING COMPONENTS FOR DISAZO DYES BASF AKTIENGESELLSCHAFT (DE) 1997-04-15 US disclosed
US-5554737-A Doubled acid azo dyes with a hydroxypyridone coupling component BASF AKTIENGESELLSCHAFT (DE) 1996-09-10 US disclosed
EP-0681004-A1 Double acid azo dyes having a hydroxypyridone-type coupler as well as their intermediate products BASF AKTIENGESELLSCHAFT (DE) 1995-11-08 EP disclosed