Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560127 | 0.83 | PTGS1 (0.47) | TSHRNPSR1ALDH1A1 | |
| SCHEMBL9890640 | 0.79 | PTGER1 (0.53) | THRATHRBRORCRORBRXRA | |
| SCHEMBL11554186 | 0.79 | MMP1 (0.41) | POLB | |
| SCHEMBL11703426 | 0.78 | FFAR4 (0.45) | THRATHRBPOLBTSHRALDH1A1 | |
| SCHEMBL11706492 | 0.77 | CAMK2A (0.38) | THRATHRB | |
| SCHEMBL11704685 | 0.77 | PTGER1 (0.41) | RXRARXRBRXRGUSP2KMO | |
| SCHEMBL11703649 | 0.76 | PTGDR2 (0.44) | POLBCHRM1ALDH1A1 | |
| SCHEMBL11707818 | 0.74 | ALOX15 (0.51) | THRATHRBRORCRORBRXRA | |
| SCHEMBL11702883 | 0.73 | MMP2 (0.45) | POLBALDH1A1 | |
| SCHEMBL11700514 | 0.73 | ALDH1A1 (0.41) | THRBRXRARXRBPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |