SCHEMBL1170959

SCHEMBL1170959

C=CC(=O)OCC(C#N)CC

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.53
HPGD P15428 1/20 0.43
ALDH1A1 P00352 6/20 0.38
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 1/20 0.38
THRB P10828 3/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23838012 0.86 TSHR (0.51) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL20475066 0.86 TSHR (0.41) TSHRHPGD
SCHEMBL4900024 0.85 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4908448 0.83 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28470539 0.82 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL27578293 0.79 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL809780 0.78 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28903788 0.77 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1958558 0.77 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL15911969 0.76 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4558530-A1 ACRYLIC COPOLYMERS IMPARTING LOW YELLOWING AFTER PHOTOCURING ARKEMA FRANCE (FR) 2025-05-28 EP claimed
EP-4558533-A1 OLIGOMERS COMPRISING POLYMERIZED HIGH-TG MONOMERS ARKEMA FRANCE (FR) 2025-05-28 EP claimed
CN-119894947-A Oligomers comprising polymerized high Tg monomers 阿科玛法国公司 2025-04-25 CN claimed
WO-2024259629-A1 MODIFIED CURRENT COLLECTOR FOR SECONDARY BATTERY GUANGDONG HAOZHI TECHNOLOGY CO. LIMITED (CN) 2024-12-26 WO claimed
CN-117457905-A Binder composition for secondary battery 中国科学院福建物质结构研究所 2024-01-26 CN claimed
WO-2024018041-A1 OLIGOMERS COMPRISING POLYMERIZED HIGH-TG MONOMERS ARKEMA FRANCE (FR) 2024-01-25 WO claimed
WO-2024018039-A1 ACRYLIC COPOLYMERS IMPARTING LOW YELLOWING AFTER PHOTOCURING ARKEMA FRANCE (FR) 2024-01-25 WO claimed
EP-4310117-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-01-24 EP claimed
CN-110233235-B Negative pole piece and electrochemical device 宁德时代新能源科技股份有限公司 2021-08-20 CN claimed
CN-109428080-B Negative electrode binder, negative electrode plate and lithium ion secondary battery 宁德时代新能源科技股份有限公司 2020-11-06 CN claimed
US-5916741-A SUPPORT WITH A HYDROPHILIC LIGHT SENSITIVE LAYER EASTMAN KODAK COMPANY (US) 1999-06-29 US claimed
US-20260022277-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2026-01-22 US disclosed
US-12404437-B2 Fiber reinforced flexible foams L&P PROPERTY MANAGEMENT COMPANY (US) 2025-09-02 US disclosed
EP-4558530-A1 ACRYLIC COPOLYMERS IMPARTING LOW YELLOWING AFTER PHOTOCURING ARKEMA FRANCE (FR) 2025-05-28 EP disclosed
EP-4558533-A1 OLIGOMERS COMPRISING POLYMERIZED HIGH-TG MONOMERS ARKEMA FRANCE (FR) 2025-05-28 EP disclosed
US-5603996-A OVANABLE CONTAINERS, WRAPPERS AND RECAPACLES A*WARE TECHNOLOGIES, L.C. (US) 1997-02-18 US disclosed
WO-1996020832-A1 COATED SHEET MATERIAL AND METHOD A*WARE TECHNOLOGIES, L.C. (US) 1996-07-11 WO disclosed
EP-0624060-A4 COATED SHEET MATERIAL AND METHOD. WARE TECHNOLOGIES L C A (US) 1995-04-05 EP disclosed
EP-0624060-A1 COATED SHEET MATERIAL AND METHOD A* WARE TECHNOLOGIES, L.C. (US) 1994-11-17 EP disclosed
WO-1993014642-A1 COATED SHEET MATERIAL AND METHOD A*WARE TECHNOLOGIES, L.C. (US) 1993-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022277-A1 CURABLE COMPOSITIONS MTDH, MYO1G, TPM3 TSHR 3126/4885HPGD 2242/4885ALDH1A1 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.