Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436722 | 0.92 | POLB (0.58) | POLBL3MBTL1TDP1CA12CA9 | |
| SCHEMBL11555586 | 0.89 | GAA (0.50) | POLBL3MBTL1TDP1CA12CA9 | |
| SCHEMBL11595388 | 0.88 | GSTO1 (0.50) | POLBL3MBTL1TDP1CA12CA9 | |
| SCHEMBL11527984 | 0.86 | GAA (0.47) | POLBL3MBTL1TDP1CA12CA9 | |
| SCHEMBL9436712 | 0.86 | GSTO1 (0.66) | POLBL3MBTL1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL9436643 | 0.84 | CA12 (0.52) | TDP1CA12CA9SMN1; SMN2KMT2A | |
| SCHEMBL11710034 | 0.83 | MAPT (0.56) | POLBL3MBTL1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL13543489 | 0.83 | MAPT (0.73) | POLBL3MBTL1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL11598345 | 0.82 | GAA (0.44) | POLBL3MBTL1TDP1CA12CA9 | |
| SCHEMBL5506453 | 0.82 | FABP4 (0.49) | TDP1CA12CA9SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |