Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710296 | 0.88 | HTT (0.52) | STING1HTTALDH1A1MEN1LMNA | |
| SCHEMBL11710682 | 0.88 | HTT (0.52) | STING1HTTALDH1A1MEN1LMNA | |
| SCHEMBL11603324 | 0.85 | THRB (0.52) | STING1HTTTHRBTHRAALDH1A1 | |
| SCHEMBL10657187 | 0.83 | THRB (0.50) | HTTTHRBTHRAALDH1A1MEN1 | |
| SCHEMBL22317250 | 0.83 | THRB (0.56) | HTTTHRBTHRAALDH1A1MEN1 | |
| SCHEMBL11460627 | 0.81 | HMGCR (0.50) | HTTTHRBTHRAALDH1A1MEN1 | |
| SCHEMBL10657116 | 0.81 | THRB (0.49) | HTTTHRBTHRAALDH1A1MEN1 | |
| SCHEMBL5056515 | 0.79 | LMNA (0.56) | STING1HTTALDH1A1MEN1LMNA | |
| SCHEMBL6931814 | 0.79 | TDP1 (0.55) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30949565 | 0.79 | TDP1 (0.55) | HTTALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003927-A | DIURETICS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |