Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11717209 | 0.99 | ERAP1 (0.53) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11709347 | 0.87 | ALDH1A1 (0.47) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Phenylpiperazine SCHEMBL11768963 | 0.87 | GPR55 (0.46) | ERAP1ALDH1A1GAAUSP2HTT | |
| SCHEMBL11711020 | 0.86 | LMNA (0.58) | ERAP1ALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL11710194 | 0.86 | WDR5 (0.49) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11711546 | 0.86 | ALDH1A1 (0.51) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11718138 | 0.86 | ALDH1A1 (0.45) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11714575 | 0.85 | ALDH1A1 (0.45) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11714398 | 0.85 | POLB (0.55) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11711366 | 0.84 | LMNA (0.47) | ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029787-A | Basically substituted 3-sulfamoylbenzoic acid derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |