Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238310 | 0.83 | HDAC8 (0.49) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL7510922 | 0.81 | HAO1 (0.49) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL1790363 | 0.81 | LMNA (0.52) | HDAC8HDAC6HDAC1SMN1; SMN2KMT2A | |
| SCHEMBL1790802 | 0.80 | MAPT (0.50) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL9709523 | 0.80 | KMT2A (0.48) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL987605 | 0.80 | HRH3 (0.43) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL233920 | 0.79 | SMN1; SMN2 (0.45) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL5185070 | 0.79 | KMT2A (0.70) | HDAC8HDAC6HDAC1SMN1; SMN2KMT2A | |
| SCHEMBL2582818 | 0.77 | THRB (0.45) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 | |
| SCHEMBL248211 | 0.77 | ALDH1A1 (0.51) | HDAC8HDAC6HDAC1HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |