Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209931 | 0.85 | TDP1 (0.67) | TDP1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL11714106 | 0.83 | KMT2A (0.51) | TDP1SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL11718996 | 0.81 | LMNA (0.52) | TDP1L3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL11716995 | 0.81 | TAS1R3 (0.49) | TDP1SMN1; SMN2L3MBTL1NPC1KMT2A | |
| SCHEMBL11715138 | 0.81 | TDP1 (0.71) | TDP1SMN1; SMN2L3MBTL1NPC1KMT2A | |
| SCHEMBL11708090 | 0.80 | RAB9A (0.47) | TDP1SMN1; SMN2L3MBTL1NPC1KMT2A | |
| SCHEMBL11717559 | 0.80 | KMT2A (0.49) | TDP1SMN1; SMN2L3MBTL1NPC1KMT2A | |
| SCHEMBL11711999 | 0.80 | L3MBTL1 (0.48) | TDP1SMN1; SMN2L3MBTL1NPC1KMT2A | |
| SCHEMBL20024745 | 0.79 | KDM4E (0.46) | TDP1L3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL11719239 | 0.78 | KDM4E (0.45) | TDP1L3MBTL1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056628-A | Insecticidal esters of alpha-phenoxy alkanoic acids with substituted benzyl alcohols | HOFFMANN-LA ROCHE INC. (US) | 1977-11-01 | — | — | US | disclosed |