SCHEMBL117131

SCHEMBL117131

CC(C)(C)c1cc(Cc2ccc(N)c(C(C)(C)C)c2)ccc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
GAA P10253 4/20 0.48
CYP3A4 P08684 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
POLB P06746 1/20 0.48
RAB9A P51151 1/20 0.48
CDC25B P30305 1/20 0.42
CASP6 P55212 1/20 0.42
RCE1 Q9Y256 1/20 0.42
TSHR P16473 4/20 0.42
ALOX15 P16050 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.37
HSPA5 P11021 1/20 0.36
CYP17A1 P05093 1/20 0.35
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2155153 0.88 POLB (0.41) ALDH1A1GAACYP3A4KDM4EMAPT
SCHEMBL2153435 0.87 SKP2 (0.41) ALDH1A1GAACYP3A4KDM4EMAPT
SCHEMBL21544165 0.80 ALDH1A1 (0.59) ALDH1A1GAAKDM4EMAPTMEN1
SCHEMBL1810720 0.78 GAA (0.48) ALDH1A1GAACYP3A4KDM4EMAPT
SCHEMBL10002079 0.77 SMN1; SMN2 (0.45) ALDH1A1GAACYP3A4KDM4EMAPT
SCHEMBL2754720 0.77 ALDH1A1 (0.33) ALDH1A1GAAKDM4E
SCHEMBL11623056 0.77 HRH3 (0.46) ALDH1A1GAAKDM4EMAPTTSHR
Hydrochloric Acid SCHEMBL11620713 0.76 HRH3 (0.44) ALDH1A1GAAKDM4EMAPTTSHR
SCHEMBL8404048 0.75 OPRL1 (0.35) ALDH1A1GAACYP3A4KDM4EMAPT
SCHEMBL2154357 0.75 PGR (0.50) ALDH1A1GAACYP3A4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12555872-B2 Polyimide coated separators, porous polyimide coatings, lithium batteries, and related methods CELGARD, LLC 2026-02-17 US claimed
EP-2220034-B1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2015-12-23 EP claimed
US-8668986-B2 Aromatic aldimines and polyurethane compositions which contain aldimine SIKA TECHNOLOGY AG (CH) 2014-03-11 US claimed
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-10-07 US claimed
EP-0335336-B1 CATALYTIC HYDROGENATION OF CRUDE METHYLENE BRIDGED POLYPHENYLAMINES TO PRODUCE POLYCYCLOHEXYLAMINES AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-08-04 EP claimed
US-5196587-A Pretreatment with ruthenium hydrogenation catalyst and then with a rhodium catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-03-23 US claimed
US-20260149126-A1 POLYIMIDE COATED SEPARATORS, POROUS POLYIMIDE COATINGS, LITHIUM BATTERIES, AND RELATED METHODS CELGARD, LLC (US) 2026-05-28 US disclosed
US-12555872-B2 Polyimide coated separators, porous polyimide coatings, lithium batteries, and related methods CELGARD, LLC 2026-02-17 US disclosed
US-20240343941-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-10-17 US disclosed
EP-3828218-B1 EPOXY RESIN, EPOXY RESIN COMPOSITION, EPOXY RESIN COMPOSITION FOR CARBON FIBER-REINFORCED COMPOSITE MATERIAL, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL NIPPONKAYAKU KK (JP) 2024-06-26 EP disclosed
US-20240199831-A1 PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2024-06-20 US disclosed
EP-4380990-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-06-12 EP disclosed
EP-3590991-B1 EPOXY RESIN COMPOSITION, PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2024-05-01 EP disclosed
WO-2000077062-A1 CLEAR, RESILIENT POLYURETHANE ELASTOMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-12-21 WO disclosed
EP-0335336-B1 CATALYTIC HYDROGENATION OF CRUDE METHYLENE BRIDGED POLYPHENYLAMINES TO PRODUCE POLYCYCLOHEXYLAMINES AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-08-04 EP disclosed
US-5196587-A Pretreatment with ruthenium hydrogenation catalyst and then with a rhodium catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-03-23 US disclosed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP disclosed
EP-0335336-A2 Catalytic hydrogenation of crude methylene bridged polyphenylamines to produce polycyclohexylamines AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-10-04 EP disclosed
US-4845283-A COATINGS, ADHESIVES, ADDITION POLYMERS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-07-04 US disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12555872-B2 Polyimide coated separators, porous polyimide coatings, lithium batteries, and related methods DCX, GABRE, DYNC1I2 ALDH1A1 4390/4885GAA 2587/4885CYP3A4 4804/4885
US-20260149126-A1 POLYIMIDE COATED SEPARATORS, POROUS POLYIMIDE COATINGS, LITHIUM BATTERIES, AND RELATED METHODS GABRE, DCX, DYNC1I2 ALDH1A1 4596/4885GAA 2241/4885CYP3A4 4809/4885
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE ODC1, DDC, SRM ALDH1A1 43/4885GAA 1814/4885CYP3A4 3591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.