Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718704 | 0.90 | DPP4 (0.48) | DPP4RAB9APTGES2PTGDR2CYP3A4 | |
| SCHEMBL11713809 | 0.84 | RAB9A (0.51) | DPP4RAB9APTGDR2 | |
| SCHEMBL11721516 | 0.82 | DPP4 (0.54) | DPP4PTGES2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11730958 | 0.76 | ALDH1A1 (0.51) | PTGDR2CYP2C9CYP2C19CYP1A2KDM4E | |
| SCHEMBL22003802 | 0.72 | HTR6 (0.56) | DPP4PTGDR2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11715698 | 0.72 | DPP4 (0.57) | DPP4PTGES2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11748287 | 0.70 | DPP4 (0.56) | DPP4PTGES2PTGDR2CYP3A4CYP2C19 | |
| SCHEMBL11719687 | 0.69 | DPP4 (0.52) | DPP4PTGES2PTGDR2KDM4E | |
| SCHEMBL8784975 | 0.69 | DPP4 (0.48) | DPP4RAB9ACYP2C9KDM4E | |
| SCHEMBL5730338 | 0.68 | RAB9A (0.47) | RAB9APTGDR2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002611-A | Preparation of benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |