Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718704 | 0.86 | DPP4 (0.48) | RAB9APTGDR2ACLYDPP4 | |
| SCHEMBL11713232 | 0.84 | DPP4 (0.45) | RAB9APTGDR2DPP4 | |
| SCHEMBL22003802 | 0.83 | HTR6 (0.56) | PTGDR2LOXL2ACLYHTR6DPP4 | |
| SCHEMBL11711942 | 0.83 | KDM4E (0.49) | PTGDR2 | |
| SCHEMBL11730958 | 0.81 | ALDH1A1 (0.51) | PTGDR2ACLY | |
| SCHEMBL11711359 | 0.80 | DPP4 (0.49) | RAB9APTGDR2LOXL2HTR6DPP4 | |
| SCHEMBL11712258 | 0.79 | PTGDR2 (0.57) | PTGDR2LOXL2KRASACLYAKR1B1 | |
| SCHEMBL27605863 | 0.73 | PTGDR2 (0.72) | PTGDR2AKR1B1PTGS1 | |
| SCHEMBL22003801 | 0.71 | PTGDR2 (0.45) | PTGDR2ACLYDPP4 | |
| SCHEMBL11715006 | 0.71 | ACLY (0.44) | RAB9APTGDR2KRASACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002611-A | Preparation of benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |