Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712171 | 0.73 | KDM4E (0.64) | KDRKDM4ECYP2C9CYP1A2IDO1 | |
| SCHEMBL10396142 | 0.73 | TGM2 (0.36) | KDM4EALDH1A1JAK3MAPKAPK2HPGD | |
| SCHEMBL10396744 | 0.70 | ALDH1A1 (0.35) | KDM4ECYP1A2ALDH1A1CDK4CCND1 | |
| SCHEMBL11717134 | 0.69 | KDM4E (0.43) | KDRKDM4ECYP2C9CYP1A2IDO1 | |
| SCHEMBL11713701 | 0.66 | CDK2 (0.39) | KDM4ECYP2C9CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11712851 | 0.66 | KDR (0.41) | KDRKDM4ECYP2C9CYP1A2IDO1 | |
| SCHEMBL549156 | 0.65 | CDK4 (0.57) | KDM4ECYP1A2ALDH1A1MAPK1CDK4 | |
| SCHEMBL11711439 | 0.64 | KDM4E (0.39) | KDRKDM4ECYP2C9CYP1A2IDO1 | |
| SCHEMBL11718132 | 0.62 | LMNA (0.41) | KDRKDM4ECYP2C9CYP1A2IDO1 | |
| SCHEMBL11718990 | 0.61 | KDM4E (0.46) | KDM4ECYP2C9CYP1A2IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |