Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27652869 | 1.00 | FFAR1 (0.63) | FFAR1FFAR4GPR84NFKB1PSMD14 | |
| Acetic Acid SCHEMBL3205436 | 0.98 | FFAR1 (0.60) | FFAR1FFAR4GPR84NFKB1PSMD14 | |
| Bicarbonate SCHEMBL28829208 | 0.94 | FFAR1 (0.66) | FFAR1FFAR4GPR84NFKB1PSMD14 | |
| Acetic Acid SCHEMBL28392186 | 0.92 | FFAR1 (0.73) | FFAR1FFAR4GPR84NFKB1FAAH | |
| Acetic Acid SCHEMBL29020019 | 0.92 | FFAR1 (0.73) | FFAR1FFAR4GPR84NFKB1FAAH | |
| Acetic Acid SCHEMBL28707278 | 0.92 | FFAR1 (0.73) | FFAR1FFAR4GPR84NFKB1FAAH | |
| Acetic Acid SCHEMBL4019504 | 0.92 | FFAR1 (0.73) | FFAR1FFAR4GPR84NFKB1FAAH | |
| Acetamide SCHEMBL8064165 | 0.90 | FFAR1 (0.56) | FFAR1FFAR4GPR84NFKB1PSMD14 | |
| Acetic Acid SCHEMBL672595 | 0.90 | FFAR1 (0.70) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL23188459 | 0.89 | FFAR4 (0.57) | FFAR1FFAR4GPR84NFKB1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400468-A1 | Bionutritional Compositions for Plants and Soils | ENVIROKURE, INCORPORATED (US) | 2024-12-05 | — | — | US | claimed |
| EP-4377280-A1 | BIONUTRITIONAL COMPOSITIONS FOR PLANTS AND SOILS | Envirokure Incorporated (US) | 2024-06-05 | — | — | EP | claimed |
| EP-4257663-A1 | FOOD CONTACT SURFACE SANITIZING LIQUID | The Procter & Gamble Company (US) | 2023-10-11 | — | — | EP | claimed |
| WO-2023009636-A1 | BIONUTRITIONAL COMPOSITIONS FOR PLANTS AND SOILS | ENVIROKURE, INCORPORATED (US) | 2023-02-02 | — | — | WO | claimed |
| CN-113201138-B | Transparent light-curable high-refractive-index mercapto silicone oil and preparation method thereof | 惠州学院 | 2022-11-22 | — | — | CN | claimed |
| CN-113201138-A | Transparent light-curable high-refractive-index mercapto silicone oil and preparation method thereof | 惠州学院 | 2021-08-03 | — | — | CN | claimed |
| WO-2018145219-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING | SERANI MOSTAZAL JORGE (CL) | 2018-08-16 | — | — | WO | claimed |
| US-9981937-B2 | Orthoformic acid esters as pro-fragrances | HENKEL AG & CO. KGAA (DE) | 2018-05-29 | — | — | US | claimed |
| US-20170349565-A1 | ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | US | claimed |
| CN-101316922-B | Stable odorant systems | THE PROCTER & GAMBLE CO. (US) | 2011-12-14 | — | — | CN | claimed |
| EP-1716159-B1 | BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-13 | — | — | EP | claimed |
| US-7579495-B2 | Active-releasing cyclic siloxanes | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-08-25 | — | — | US | claimed |
| US-7576170-B2 | Cyclic siloxane compositions for the release of active ingredients | MOMENTIVE PERFORMANCE MATERIALS (US) | 2009-08-18 | — | — | US | claimed |
| EP-1697386-B1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GEN ELECTRIC (US) | 2007-10-10 | — | — | EP | claimed |
| EP-1716159-A2 | CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | General Electronic Company (US) | 2006-11-02 | — | — | EP | claimed |
| EP-1697386-A1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | General Electric Company A Corporation of the State of New York (US) | 2006-09-06 | — | — | EP | claimed |
| WO-2005066187-A1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GENERAL ELECTRIC COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| WO-2005066186-A2 | CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | GENERAL ELECTRIC COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| US-20050136021-A1 | Active-releasing cyclic siloxanes | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-06-23 | — | — | US | claimed |
| US-20050136022-A1 | Cyclic siloxane compositions for the release of active ingredients | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349565-A1 | ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES | FAAH, NISCH, ELOVL6 | FFAR1 9/4885FFAR4 39/4885GPR84 356/4885 |
| US-20050136022-A1 | Cyclic siloxane compositions for the release of active ingredients | F9, RPL39, ECPAS | FFAR1 320/4885FFAR4 1009/4885GPR84 651/4885 |
| US-20050136021-A1 | Active-releasing cyclic siloxanes | F9, RPL39, ALDH16A1 | FFAR1 179/4885FFAR4 702/4885GPR84 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.