Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | MMP9 | P14780 | 4/20 | 0.57 |
| ▸ | MMP8 | P22894 | 4/20 | 0.57 |
| ▸ | MMP13 | P45452 | 4/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058514 | 0.92 | RAB9A (0.66) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL11715691 | 0.84 | RAB9A (0.56) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL2245362 | 0.79 | RAB9A (0.64) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL2245219 | 0.78 | MMP2 (0.85) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL11717472 | 0.78 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL7908000 | 0.77 | RAB9A (0.84) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL11768156 | 0.77 | RAB9A (0.62) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL2060733 | 0.77 | ALDH1A1 (0.61) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL11718804 | 0.77 | RAB9A (0.58) | RAB9ANPC1MAPTSMN1; SMN2MMP2 | |
| SCHEMBL11718002 | 0.77 | CTSB (0.49) | RAB9ANPC1MAPTSMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022781-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3985755-A | ANTHELMINTIC AGENTS AND DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3983130-A | ANTHELMINTICS, DISINFECTANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3969351-A | ANTHELMINTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |