Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951808 | 0.78 | KMT2A (0.43) | KMT2AMAPTGAAMEN1ALOX15 | |
| SCHEMBL14800110 | 0.75 | ALDH1A1 (0.48) | KMT2AMAPTGAAMEN1HPGD | |
| SCHEMBL11044723 | 0.74 | CSNK2A1 (0.55) | KMT2AMAPTGAAMEN1ALOX15 | |
| SCHEMBL6506883 | 0.74 | HTT (0.43) | KMT2AMAPTGAAMEN1HSD17B10 | |
| SCHEMBL9770532 | 0.74 | ALOX15 (0.50) | MAPTGAAALOX15HSD17B10TP53 | |
| SCHEMBL8172784 | 0.72 | KMT2A (0.42) | KMT2AMAPTGAAMEN1ALOX15 | |
| SCHEMBL6843558 | 0.72 | ALDH1A1 (0.39) | MAPTGAAALOX15HSD17B10HPGD | |
| SCHEMBL11261432 | 0.71 | ALOX15 (0.48) | KMT2AMAPTGAAMEN1ALOX15 | |
| SCHEMBL10147428 | 0.71 | TDP1 (0.44) | KMT2AGAAMEN1ALOX15HSD17B10 | |
| SCHEMBL28822007 | 0.71 | PARP1 (0.42) | KMT2AMAPTGAAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008264-A | Process for the preparation of aromatic thiocarboxylic acid amides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | disclosed |