Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26088044 | 0.78 | KMT2A (0.48) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL26930708 | 0.77 | NOD2 (0.47) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL30708803 | 0.77 | NOD2 (0.47) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL21408425 | 0.77 | NPSR1 (0.48) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL21408332 | 0.77 | NPSR1 (0.45) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL24749034 | 0.76 | GLA (0.42) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8401817 | 0.74 | ALDH1A1 (0.50) | L3MBTL1LMNAALDH1A1RAB9AMAPT | |
| SCHEMBL11486363 | 0.74 | CXCL8 (0.44) | KDM4EL3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL11359782 | 0.74 | TSHR (0.56) | KDM4ETSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL11714097 | 0.74 | FNTA (0.44) | KDM4ELMNAALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048191-A | Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-13 | — | — | US | disclosed |