Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403244 | 0.84 | NPSR1 (0.50) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL8399672 | 0.82 | F2 (0.44) | ALDH1A1LMNASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL8403364 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNACXCL8AKR1B1PTGS1 | |
| SCHEMBL257469 | 0.78 | ATM (0.44) | ALDH1A1LMNACXCL8AKR1B1PTGS1 | |
| SCHEMBL8404830 | 0.77 | CXCL8 (0.61) | ALDH1A1LMNACXCL8AKR1B1PTGS1 | |
| SCHEMBL11715181 | 0.74 | KDM4E (0.50) | ALDH1A1LMNACXCL8AKR1B1PTGS1 | |
| SCHEMBL8401935 | 0.72 | BCL2L11 (0.48) | LMNASMN1; SMN2KMT2AHTTRAB9A | |
| SCHEMBL10936763 | 0.71 | CXCL8 (0.64) | ALDH1A1LMNACXCL8AKR1B1PTGS1 | |
| SCHEMBL10811376 | 0.71 | CXCL8 (0.67) | ALDH1A1LMNACXCL8AKR1B1PTGS1 | |
| SCHEMBL8845773 | 0.71 | ALDH1A1 (0.64) | ALDH1A1LMNAPTGS2HPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |