Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713752 | 0.89 | OPRK1 (0.50) | OPRK1PDE4DADRA1ANR1I2ADORA3 | |
| SCHEMBL11716883 | 0.87 | OPRK1 (0.67) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11680057 | 0.80 | OPRK1 (0.76) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11468031 | 0.75 | OPRK1 (0.48) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL7873579 | 0.74 | OPRK1 (0.48) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11681691 | 0.74 | OPRK1 (0.47) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11460072 | 0.73 | SMARCA2 (0.52) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11458720 | 0.73 | SMARCA2 (0.52) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11480381 | 0.73 | SMARCA2 (0.52) | GABRA1GABRA5GABRA2OPRK1PDE4D | |
| SCHEMBL11614249 | 0.73 | GABRA1 (0.49) | GABRA1GABRA5GABRA2OPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002611-A | Preparation of benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |