Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HBB | P68871 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | LTK | P29376 | 2/20 | 0.37 |
| ▸ | PRKX | P51817 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716102 | 0.83 | PKM (0.35) | KMT2ALMNASIGMAR1 | |
| SCHEMBL11715464 | 0.81 | PDK2 (0.36) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL11720987 | 0.79 | PARK7 (0.37) | KDM4EMAPTMAPK1PDK2L3MBTL1 | |
| SCHEMBL11721089 | 0.79 | GABRA1 (0.33) | SIGMAR1 | |
| SCHEMBL11719254 | 0.79 | PGR (0.38) | PDK2HTR7 | |
| SCHEMBL11714685 | 0.79 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAPTPDK2 | |
| SCHEMBL11717678 | 0.77 | PDK2 (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL11715657 | 0.77 | NOX1 (0.33) | MEN1KMT2AALDH1A1DRD3NOX1 | |
| SCHEMBL11719488 | 0.76 | PTGER4 (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11713825 | 0.76 | PGR (0.42) | PDK2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064139-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, ANTI-PARKINSON'S DISEASE | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-4064139-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, ANTI-PARKINSON'S DISEASE | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |