Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720201 | 0.93 | LMNA (0.38) | CDK4CCND1GSK3BALDH1A1UTS2R | |
| SCHEMBL11711347 | 0.91 | TP53 (0.40) | TP53KDM4EGAACDK4CCND1 | |
| SCHEMBL11715783 | 0.90 | KDM4E (0.37) | TP53KDM4EGAACDK4CCND1 | |
| SCHEMBL11715694 | 0.90 | CDK4 (0.37) | KDM4EGAACDK4CCND1GSK3B | |
| SCHEMBL11717020 | 0.88 | KDM4E (0.39) | TP53KDM4EGAACDK4CCND1 | |
| SCHEMBL11710089 | 0.87 | ALDH1A1 (0.37) | TP53KDM4EGAAALDH1A1ELANE | |
| SCHEMBL11711439 | 0.86 | KDM4E (0.39) | KDM4EGAACDK4CCND1GSK3B | |
| SCHEMBL11712722 | 0.85 | LMNA (0.41) | KDM4EALDH1A1UTS2RELANELMNA | |
| SCHEMBL11713383 | 0.85 | GSK3B (0.36) | CDK4CCND1GSK3BALDH1A1UTS2R | |
| SCHEMBL11714396 | 0.81 | PTGER4 (0.38) | TP53KDM4EGAACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |