Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715783 | 0.94 | KDM4E (0.37) | TP53KDM4EGAAPTGER4ALDH1A1 | |
| SCHEMBL11715552 | 0.91 | TP53 (0.36) | TP53KDM4EGAAALDH1A1ELANE | |
| SCHEMBL11717020 | 0.91 | KDM4E (0.39) | TP53KDM4EGAAPTGER4ALDH1A1 | |
| SCHEMBL11712722 | 0.89 | LMNA (0.41) | KDM4EPTGER4ALDH1A1ELANETOP2A | |
| SCHEMBL11710089 | 0.88 | ALDH1A1 (0.37) | TP53KDM4EGAAPTGER4ALDH1A1 | |
| SCHEMBL11712853 | 0.87 | PTGER4 (0.37) | TP53KDM4EPTGER4ALDH1A1CDK4 | |
| SCHEMBL11711439 | 0.87 | KDM4E (0.39) | KDM4EGAAPTGER4ALDH1A1ELANE | |
| SCHEMBL11714396 | 0.85 | PTGER4 (0.38) | TP53KDM4EGAAPTGER4ALDH1A1 | |
| SCHEMBL11720201 | 0.84 | LMNA (0.38) | PTGER4ALDH1A1ELANETOP2ALMNA | |
| SCHEMBL11719736 | 0.84 | KDM4E (0.38) | TP53KDM4EGAAALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |