Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715783 | 0.94 | KDM4E (0.37) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11718278 | 0.92 | ALDH1A1 (0.35) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11712722 | 0.90 | LMNA (0.41) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11713977 | 0.89 | METAP2 (0.36) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11711347 | 0.88 | TP53 (0.40) | ALDH1A1LMNAKDM4ESMN1; SMN2PTGER4 | |
| SCHEMBL11715552 | 0.87 | TP53 (0.36) | ALDH1A1LMNAKDM4EMAPTHTT | |
| SCHEMBL11714396 | 0.86 | PTGER4 (0.38) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL11720201 | 0.85 | LMNA (0.38) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL11717020 | 0.85 | KDM4E (0.39) | ALDH1A1LMNAKDM4ESMN1; SMN2TSHR | |
| SCHEMBL11716329 | 0.82 | LMNA (0.43) | ALDH1A1LMNASMN1; SMN2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |