Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.40 |
| ▸ | F13A1 | P00488 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11251505 | 0.98 | LTB4R (0.40) | LTB4RF13A1RXFP1MAPTTSHR | |
| SCHEMBL11719884 | 0.88 | LTB4R (0.39) | LTB4RF13A1RXFP1MAPTLMNA | |
| SCHEMBL11720804 | 0.86 | LTB4R (0.38) | LTB4RF13A1RXFP1MAPTLMNA | |
| SCHEMBL11259455 | 0.85 | SMN1; SMN2 (0.41) | LTB4RF13A1RXFP1MAPTLMNA | |
| SCHEMBL9686955 | 0.84 | PPARA (0.41) | TSHR | |
| SCHEMBL11720544 | 0.79 | POLB (0.34) | LTB4RMAPTALDH1A1TSHR | |
| SCHEMBL3221087 | 0.78 | GABRP (0.37) | MAPTALDH1A1TSHR | |
| SCHEMBL11722474 | 0.75 | LTB4R (0.36) | LTB4RF13A1RXFP1MAPT | |
| SCHEMBL3084169 | 0.74 | GABRP (0.40) | MAPTALDH1A1TSHR | |
| SCHEMBL11718479 | 0.74 | LTB4R (0.39) | LTB4RF13A1RXFP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029647-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-3978084-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1976-08-31 | — | — | US | disclosed |