Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722409 | 0.82 | POLB (0.36) | POLBTDP1MAPTNPC1RAB9A | |
| SCHEMBL11259455 | 0.82 | SMN1; SMN2 (0.41) | POLBTDP1TSHRMAPTNPC1 | |
| SCHEMBL11716144 | 0.79 | LTB4R (0.40) | TSHRMAPTALDH1A1LTB4R | |
| Hydrochloric Acid SCHEMBL11251505 | 0.77 | LTB4R (0.40) | TSHRMAPTLTB4R | |
| SCHEMBL11720804 | 0.75 | LTB4R (0.38) | MAPTALDH1A1LTB4R | |
| SCHEMBL3219948 | 0.73 | HSP90AA1 (0.48) | POLBTSHRMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11109077 | 0.72 | ALDH1A1 (0.48) | POLBTDP1TSHRMAPTNPC1 | |
| SCHEMBL11255526 | 0.71 | HPGD (0.41) | POLBTSHRMAPTNPC1RAB9A | |
| SCHEMBL9724742 | 0.71 | KDM4E (0.42) | POLBTDP1TSHRMAPTKMT2A | |
| SCHEMBL9686955 | 0.70 | PPARA (0.41) | TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029647-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-3978084-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1976-08-31 | — | — | US | disclosed |