Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951339 | 0.90 | CA1 (0.56) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL15358099 | 0.87 | ALDH1A1 (0.51) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL10918857 | 0.85 | CA1 (0.55) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL7762382 | 0.84 | CA1 (0.51) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL29039368 | 0.84 | CA1 (0.51) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL1817672 | 0.84 | CA1 (0.51) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL8127146 | 0.83 | CYP4F2 (0.55) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL23774898 | 0.83 | GAA (0.54) | ALDH1A1HSD17B10GAATSHRKMT2A | |
| SCHEMBL30508547 | 0.81 | CA1 (0.51) | CYP4F2CYP4A11CA1CA2CA12 | |
| SCHEMBL4681116 | 0.81 | CA1 (0.51) | CYP4F2CYP4A11CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018814-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-4013676-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3996247-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |