SCHEMBL10918857

SCHEMBL10918857

CCOC(=O)c1cc(N)c(Cl)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA12 O43570 3/20 0.55
CA9 Q16790 3/20 0.55
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP4F2 P78329 1/20 0.53
CYP4A11 Q02928 1/20 0.53
BAZ2B Q9UIF8 1/20 0.53
BAZ2A Q9UIF9 1/20 0.53
GAA P10253 2/20 0.47
MAPK1 P28482 1/20 0.47
TSHR P16473 2/20 0.47
HTR4 Q13639 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
HTR3A P46098 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11951339 0.91 CA1 (0.56) CA1CA2CA12CA9ALDH1A1
SCHEMBL9710977 0.85 ALDH1A1 (0.49) CA1CA2CA12CA9ALDH1A1
SCHEMBL4681116 0.85 CA1 (0.51) CA1CA2CA12CA9ALDH1A1
SCHEMBL30508547 0.85 CA1 (0.51) CA1CA2CA12CA9ALDH1A1
SCHEMBL11716438 0.85 CYP4F2 (0.55) CA1CA2CA12CA9ALDH1A1
SCHEMBL11725048 0.85 ALDH1A1 (0.51) CA1CA2CA12CA9ALDH1A1
SCHEMBL29039368 0.82 CA1 (0.51) CA1CA2CA12CA9ALDH1A1
SCHEMBL1817672 0.82 CA1 (0.51) CA1CA2CA12CA9ALDH1A1
SCHEMBL7762382 0.82 CA1 (0.51) CA1CA2CA12CA9ALDH1A1
SCHEMBL17008980 0.82 CA1 (0.48) CA1CA2CA12CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104532-B1 O-HALOBENZOIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS AND THEIR USE Nippon Kayaku Kabushiki Kaisha (JP) 1986-12-03 EP disclosed
US-4561880-A 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1985-12-31 US disclosed
US-4531964-A Heterocyclic compound and a herbicidal composition containing said compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1985-07-30 US disclosed
EP-0104532-A1 O-Halobenzoic acid derivatives, process for their preparation, herbicidal compositions and their use Nippon Kayaku Kabushiki Kaisha (JP) 1984-04-04 EP disclosed
EP-0104484-A1 A heterocyclic compound and its use as herbicide Nippon Kayaku Kabushiki Kaisha (JP) 1984-04-04 EP disclosed