SCHEMBL29039368

SCHEMBL29039368

CCOC(=O)c1cc(F)c(N)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA12 O43570 1/20 0.51
CA9 Q16790 1/20 0.51
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
BAZ2B Q9UIF8 1/20 0.49
BAZ2A Q9UIF9 1/20 0.49
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 3/20 0.46
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.43
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4681116 0.94 CA1 (0.51) CA1CA2CA12CA9CYP4F2
SCHEMBL30508547 0.94 CA1 (0.51) CA1CA2CA12CA9CYP4F2
SCHEMBL9573792 0.88 ALDH1A1 (0.49) CA1CA2CA12CA9CYP4F2
SCHEMBL11951339 0.87 CA1 (0.56) CA1CA2CA12CA9CYP4F2
SCHEMBL2549970 0.87 LMNA (0.60) CA1CA2CA12CA9CYP4F2
SCHEMBL2596428 0.85 ALDH1A1 (0.53) CA1CA2CA12CA9ALDH1A1
SCHEMBL8335693 0.85 CYP4F2 (0.53) CA1CA2CA12CA9CYP4F2
SCHEMBL25286223 0.84 GAA (0.50) CA1CA2CA12CA9CYP4F2
SCHEMBL30987200 0.84 GAA (0.50) CA1CA2CA12CA9CYP4F2
SCHEMBL11716438 0.84 CYP4F2 (0.55) CA1CA2CA12CA9CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116462631-A Synthetic method of norfloxacin 青海夏都医药有限公司 2023-07-21 CN disclosed