Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2274722 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1HPSEXDHKMT2A | |
| SCHEMBL11716990 | 0.78 | CRHBP (0.53) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL21072635 | 0.78 | XDH (0.58) | KDM4EALDH1A1HPSEXDHTDP1 | |
| SCHEMBL27354736 | 0.77 | PARP10 (0.50) | KDM4EF10ALDH1A1HPSEXDH | |
| SCHEMBL10717379 | 0.77 | ALDH1A1 (0.55) | KDM4EALDH1A1HPSEXDHKMT2A | |
| SCHEMBL1602832 | 0.76 | MAPK1 (0.51) | KDM4EALDH1A1HPSEXDHKMT2A | |
| SCHEMBL476349 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AMEN1TTR | |
| SCHEMBL10548093 | 0.75 | CTSD (0.56) | ALDH1A1KMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL13646974 | 0.75 | CTSD (0.56) | ALDH1A1KMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL2270511 | 0.75 | XDH (0.46) | KDM4EALDH1A1HPSEXDHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003909-A | [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |