Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613198 | 0.83 | CACNA1G (0.42) | MEN1KMT2A | |
| SCHEMBL9721752 | 0.79 | TDP1 (0.47) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL11610509 | 0.74 | TAAR1 (0.41) | L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL9721837 | 0.71 | CXCL12 (0.44) | DRD2DRD4DRD3KDM4ESMN1; SMN2 | |
| SCHEMBL9114592 | 0.71 | CYP1A2 (0.63) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL19862541 | 0.71 | TDP1 (0.66) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL8815738 | 0.70 | DRD2 (0.44) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL4403318 | 0.69 | MMP12 (0.47) | TDP1L3MBTL1KDM4ESMN1; SMN2LTA4H | |
| SCHEMBL10338308 | 0.69 | MEN1 (0.60) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL1310073 | 0.68 | LTA4H (0.50) | DRD2DRD4DRD3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |