Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712294 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11713467 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11711407 | 0.83 | CASP3 (0.51) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL11720863 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11720175 | 0.83 | CASP3 (0.45) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11708220 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11710437 | 0.82 | PARP1 (0.48) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL11712171 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11715038 | 0.74 | PRKCB (0.47) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL11714771 | 0.72 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |