Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710437 | 0.93 | PARP1 (0.48) | MEN1KMT2APABPC1PARP1NPC1 | |
| SCHEMBL11712886 | 0.84 | CASP3 (0.46) | CASP3MEN1KMT2APABPC1CCR6 | |
| SCHEMBL11711407 | 0.84 | CASP3 (0.51) | CASP3MEN1KMT2APABPC1NPC1 | |
| SCHEMBL11717971 | 0.83 | CASP3 (0.45) | CASP3MEN1KMT2APABPC1CCR6 | |
| SCHEMBL11718990 | 0.83 | KDM4E (0.46) | CASP3MEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL11712294 | 0.80 | KDM4E (0.41) | CASP3MEN1KMT2ACCR6ATM | |
| SCHEMBL11720863 | 0.78 | ALDH1A1 (0.48) | HKDC1LMNAALDH1A1 | |
| SCHEMBL11715038 | 0.69 | PRKCB (0.47) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL11365351 | 0.69 | HSP90AA1 (0.56) | CASP3MEN1KMT2APABPC1CCR6 | |
| SCHEMBL5334328 | 0.67 | CDK4 (0.44) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |