Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 12/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722636 | 0.84 | ALDH1A1 (0.51) | KDRMAPTALDH1A1NPC1RECQL | |
| SCHEMBL11727105 | 0.82 | MMP2 (0.48) | KDRMAPTALDH1A1NPC1RECQL | |
| SCHEMBL11725236 | 0.79 | MMP2 (0.51) | KDRMAPTALDH1A1NPC1RECQL | |
| SCHEMBL11723310 | 0.76 | GLA (0.46) | GLAEGFRERBB2KDRMAPT | |
| SCHEMBL4277260 | 0.76 | ACHE (0.55) | KDR | |
| SCHEMBL677158 | 0.75 | GLA (0.78) | GLAEGFRERBB2MAPTALDH1A1 | |
| SCHEMBL11824972 | 0.74 | EGFR (0.58) | GLAEGFRERBB2MAPTALDH1A1 | |
| SCHEMBL11724259 | 0.71 | EGFR (0.41) | GLAEGFRERBB2KDRMAPT | |
| SCHEMBL11613846 | 0.70 | GLA (0.56) | GLAEGFRERBB2MAPTALDH1A1 | |
| SCHEMBL11724706 | 0.70 | GLA (0.51) | GLAEGFRERBB2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |