Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433337 | 0.82 | ALDH1A1 (0.63) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL31390541 | 0.82 | ALDH1A1 (0.63) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL11716323 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL11717150 | 0.80 | NPSR1 (0.63) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL11723980 | 0.79 | ALDH1A1 (0.60) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL11784892 | 0.79 | KDM4E (0.79) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL5485870 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL10470169 | 0.76 | RAB9A (0.59) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL10469568 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 | |
| SCHEMBL5479421 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1NPSR1CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013670-A | ANTIARRHYTHMICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | claimed |