Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977291 | 0.86 | EP300 (0.41) | GLO1ALDH1A1TDP1TSHRTHPO | |
| SCHEMBL9397758 | 0.80 | GLO1 (0.43) | GLO1ALDH1A1LMNA | |
| SCHEMBL9397761 | 0.80 | GLO1 (0.43) | GLO1ALDH1A1LMNA | |
| SCHEMBL4147579 | 0.78 | GLO1 (0.69) | GLO1ALDH1A1TDP1MAPK1KDM4E | |
| SCHEMBL17950855 | 0.78 | GLO1 (0.33) | GLO1 | |
| SCHEMBL4147576 | 0.78 | GLO1 (0.69) | GLO1ALDH1A1TDP1MAPK1KDM4E | |
| SCHEMBL11722149 | 0.77 | EP300 (0.43) | GLO1ALDH1A1TDP1TSHRTHPO | |
| SCHEMBL18951736 | 0.77 | CYP2C9 (0.34) | GLO1 | |
| SCHEMBL190066 | 0.75 | EP300 (0.52) | ALDH1A1TDP1GRIK1GRIK2MAPK1 | |
| SCHEMBL14712303 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025537-A | Preparation of 3-carboalkoxy or 3-alkanoyl furans | KRETCHMER RICHARD ALLAN | 1977-05-24 | — | — | US | disclosed |