Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397761 | 1.00 | GLO1 (0.43) | GLO1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5918757 | 0.88 | ALDH1A1 (0.36) | GLO1ALDH1A1TET2EGLN1MAPT | |
| SCHEMBL10456521 | 0.82 | EP300 (0.38) | ALDH1A1TET2EGLN1 | |
| SCHEMBL4147576 | 0.80 | GLO1 (0.69) | GLO1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4147579 | 0.80 | GLO1 (0.69) | GLO1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11720316 | 0.80 | GLO1 (0.42) | GLO1ALDH1A1LMNA | |
| SCHEMBL8099809 | 0.78 | EP300 (0.53) | GLO1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7792307 | 0.78 | EP300 (0.53) | GLO1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7104542 | 0.77 | MAPT (0.32) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL7104544 | 0.77 | MAPT (0.32) | ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298619-A | Platelet activating factor, antiinflammatory agents, allergens and for immunodeficient syndromes | ALTER, S.A. (ES) | 1994-03-29 | — | — | US | disclosed |
| EP-0531598-A1 | 1,4-Dihydropyridines with paf-antagonistic activity | ALTER, S.A. (ES) | 1993-03-17 | — | — | EP | disclosed |