Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727612 | 0.83 | KDM4E (0.50) | MAPTLMNAGAACYP2C19PKM | |
| SCHEMBL31226521 | 0.83 | GAA (0.50) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL11723199 | 0.81 | MAPT (0.50) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL12410537 | 0.80 | MEN1 (0.68) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL11724159 | 0.78 | THRB (0.47) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL17080656 | 0.78 | LMNA (0.52) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL11720739 | 0.76 | ALDH1A1 (0.39) | MAPTLMNAGAAKMT2AL3MBTL1 | |
| SCHEMBL11723976 | 0.75 | GAA (0.46) | MAPTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11718691 | 0.75 | GAA (0.50) | MAPTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11719928 | 0.75 | KMT2A (0.51) | MAPTGAAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |