Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31226521 | 0.86 | GAA (0.50) | POLBMAPTGAASMN1; SMN2ATM | |
| SCHEMBL11723199 | 0.85 | MAPT (0.50) | KDM4EPOLBMAPTGAASMN1; SMN2 | |
| SCHEMBL5506840 | 0.84 | PKM (0.63) | POLBMAPTGAAALOX12SMN1; SMN2 | |
| SCHEMBL11720524 | 0.83 | MAPT (0.48) | KDM4EMAPTGAASMN1; SMN2ATM | |
| SCHEMBL11724159 | 0.81 | THRB (0.47) | KDM4EPOLBMAPTGAASMN1; SMN2 | |
| SCHEMBL11720670 | 0.81 | ALDH1A1 (0.54) | KDM4EMAPTGAAALOX12SMN1; SMN2 | |
| SCHEMBL5507075 | 0.80 | ALDH1A1 (0.70) | POLBGAAALOX12SMN1; SMN2HDAC3 | |
| SCHEMBL9734781 | 0.79 | PKM (0.64) | MAPTGAAALOX12HDAC3HDAC1 | |
| SCHEMBL9733961 | 0.79 | PKM (0.64) | MAPTGAAALOX12HDAC3HDAC1 | |
| SCHEMBL9169640 | 0.79 | PKM (0.60) | MAPTGAAALOX12SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |