Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843864 | 0.79 | NOTUM (0.56) | NOTUMAVPR2AVPR1ASRD5A1HDAC1 | |
| SCHEMBL4520413 | 0.76 | NOTUM (0.62) | NOTUMTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8553135 | 0.75 | BMPR1B (0.46) | SRD5A1ALDH1A1MAPT | |
| SCHEMBL9442261 | 0.73 | NOTUM (0.59) | NOTUMSRD5A1HDAC1HDAC8HDAC6 | |
| SCHEMBL4514374 | 0.72 | NOTUM (0.69) | NOTUMTP53KDM4EALDH1A1MAPT | |
| SCHEMBL2061464 | 0.71 | ATAD2 (0.47) | NOTUMAVPR2AVPR1AKDM4EALDH1A1 | |
| SCHEMBL27656558 | 0.69 | SMN1; SMN2 (0.38) | NOTUMALDH1A1L3MBTL1POLB | |
| SCHEMBL6690377 | 0.69 | PDE5A (0.67) | NOTUMPDE5AKDM4ESRD5A1ALDH1A1 | |
| SCHEMBL6199079 | 0.68 | NOTUM (0.72) | NOTUMKDM4EALDH1A1L3MBTL1HSD17B3 | |
| SCHEMBL8554279 | 0.68 | CYP11B2 (0.51) | SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008267-A | ANALYZING | AB KABI (SW) | 1977-02-15 | — | — | US | disclosed |