Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620020 | 0.86 | MAPT (0.69) | MAPTNPC1MEN1KMT2AHTT | |
| SCHEMBL11574421 | 0.85 | TDP1 (0.51) | MAPTNPC1KMT2AMAPK1POLB | |
| SCHEMBL11568718 | 0.84 | NPC1 (0.48) | MAPTNPC1POLBRAB9ATHRB | |
| SCHEMBL11725068 | 0.75 | TP53 (0.46) | MAPT | |
| Water SCHEMBL11565814 | 0.74 | MAPT (0.50) | MAPTMEN1KMT2AHTTPOLB | |
| SCHEMBL11574037 | 0.73 | ALDH1A1 (0.52) | MAPTNPC1MEN1KMT2APOLB | |
| SCHEMBL11574023 | 0.73 | NPC1 (0.46) | NPC1POLBRAB9ATHRBMTNR1A | |
| SCHEMBL11209876 | 0.73 | RORC (0.49) | RORCMEN1KMT2AMAPK1POLB | |
| SCHEMBL11465129 | 0.72 | MAPT (0.68) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL3364884 | 0.72 | POLB (0.60) | MAPTKMT2APOLBTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |