Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Megazol SCHEMBL11696315 | 0.77 | MGAM (0.46) | RXFP1ALDH1A1MAPK1PKMSMN1; SMN2 | |
| SCHEMBL11695276 | 0.76 | ALDH1A1 (0.38) | RXFP1ALDH1A1MAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL11696459 | 0.74 | LMNA (0.37) | RXFP1ALDH1A1MAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL11669426 | 0.71 | PIM1 (0.57) | ALDH1A1MAPK1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2484996 | 0.70 | PTGS1 (0.39) | ALDH1A1MAPK1SMN1; SMN2CYP2C19MAPT | |
| SCHEMBL27613658 | 0.69 | CYP2C19 (0.43) | RXFP1ALDH1A1MAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL11725800 | 0.67 | CYP2C19 (0.36) | RXFP1ALDH1A1MAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL11725791 | 0.67 | CYP2C19 (0.36) | RXFP1ALDH1A1MAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL14739954 | 0.65 | MEN1 (0.32) | RXFP1ALDH1A1MAPK1CYP2C19MAPT | |
| SCHEMBL11840357 | 0.65 | CYP2C19 (0.38) | RXFP1ALDH1A1MAPK1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-3991200-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1976-11-09 | — | — | US | disclosed |