Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731552 | 0.89 | HPGD (0.45) | TDP1CYP1A2HPGDKMT2AALDH1A1 | |
| SCHEMBL11728728 | 0.89 | ALDH1A1 (0.40) | TDP1KMT2AALDH1A1MAPK1ALOX5 | |
| SCHEMBL11733336 | 0.88 | CYP1A2 (0.48) | TDP1CYP1A2GAACYP2C19HPGD | |
| SCHEMBL11730758 | 0.86 | TDP1 (0.45) | TDP1KMT2AALDH1A1MAPK1ALOX5 | |
| SCHEMBL11732380 | 0.85 | GRM2 (0.38) | TDP1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11730168 | 0.83 | TBXA2R (0.46) | TDP1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11726052 | 0.82 | FAAH (0.40) | TDP1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11852601 | 0.81 | ALOX15 (0.40) | GAAALDH1A1 | |
| SCHEMBL11730979 | 0.81 | HPGD (0.44) | TDP1HPGDKMT2AALDH1A1MAPK1 | |
| SCHEMBL11728727 | 0.80 | ALDH1A1 (0.48) | TDP1KMT2AALDH1A1MAPK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |