Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11726696 | 0.72 | SLC6A2 (0.45) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Demelverine SCHEMBL7778459 | 0.69 | SIGMAR1 (0.63) | SIGMAR1KMT2ATAAR1FDPSTHRA | |
| Maleic Acid SCHEMBL11725036 | 0.68 | LTB4R (0.39) | SIGMAR1KMT2ATAAR1FDPSTHRA | |
| Demelverine SCHEMBL1516521 | 0.67 | SIGMAR1 (0.76) | SIGMAR1TAAR1FDPSSLC6A2SLC6A4 | |
| SCHEMBL9768687 | 0.66 | SIGMAR1 (0.73) | SIGMAR1TAAR1FDPSSLC6A2SLC6A4 | |
| Oxalic Acid SCHEMBL8090960 | 0.66 | SIGMAR1 (0.68) | SIGMAR1THRATHRB | |
| Hydrochloric Acid SCHEMBL9553898 | 0.64 | LTA4H (0.57) | SIGMAR1KMT2ATAAR1FDPSSLC6A3 | |
| Oxalic Acid SCHEMBL10689565 | 0.64 | TAAR1 (0.49) | SIGMAR1KMT2ATAAR1FDPSTHRA | |
| SCHEMBL17931602 | 0.64 | TAAR1 (0.55) | SIGMAR1KMT2ATAAR1FDPSTHRA | |
| SCHEMBL1520363 | 0.63 | KMT2A (0.59) | KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061637-A | CNS, CARDIOVASCULAR, ANTIINFLAMMATORY, ADRENOLYTIC, ANTIULCER | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1977-12-06 | — | — | US | disclosed |