Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | TYMS | P04818 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621303 | 0.89 | CYP3A4 (0.54) | DPP4ANPEPTYMSLMNACYP3A4 | |
| SCHEMBL11727066 | 0.88 | DPP4 (0.55) | DPP4ANPEPTYMSLMNAMEN1 | |
| SCHEMBL18806460 | 0.87 | CYP3A4 (0.61) | DPP4ANPEPLMNAMEN1KMT2A | |
| SCHEMBL14906064 | 0.84 | CYP3A4 (0.71) | DPP4ANPEPTYMSCYP3A4NFKB1 | |
| SCHEMBL9468867 | 0.79 | ADORA2A (0.67) | DPP4TYMSLMNAMEN1KMT2A | |
| SCHEMBL11726873 | 0.79 | LMNA (0.61) | DPP4TYMSLMNAMEN1KMT2A | |
| SCHEMBL11842766 | 0.78 | CA2 (0.47) | DPP4ANPEPLMNAMEN1KMT2A | |
| SCHEMBL11621300 | 0.77 | CYP3A4 (0.57) | DPP4ANPEPLMNACYP3A4NFKB1 | |
| SCHEMBL11721611 | 0.77 | ALDH1A1 (0.62) | DPP4ANPEPLMNAMEN1KMT2A | |
| SCHEMBL10658930 | 0.75 | ANPEP (0.69) | DPP4ANPEPLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3941883-A | Aromatic dicarboxamides as anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |