Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TYMS | P04818 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | BRD1 | O95696 | 1/20 | 0.47 |
| ▸ | TAF1 | P21675 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726856 | 0.90 | LMNA (0.61) | LMNARECQLTYMSSCN2APOLB | |
| SCHEMBL11619096 | 0.89 | LMNA (0.54) | LMNARECQLSCN2AL3MBTL1POLB | |
| SCHEMBL18806465 | 0.88 | RECQL (0.62) | LMNARECQLSCN2AL3MBTL1POLB | |
| SCHEMBL14893998 | 0.86 | LMNA (0.54) | LMNARECQLTYMSSCN2APOLB | |
| SCHEMBL11825666 | 0.80 | ALDH1A1 (0.47) | LMNARECQLL3MBTL1MEN1CASP6 | |
| SCHEMBL11727082 | 0.79 | DPP4 (0.55) | LMNATYMSMEN1KMT2ADPP4 | |
| SCHEMBL11619089 | 0.79 | LMNA (0.54) | LMNARECQLSCN2APOLBBRD1 | |
| SCHEMBL11726838 | 0.78 | CA12 (0.50) | LMNARECQLSCN2AL3MBTL1POLB | |
| SCHEMBL9500252 | 0.77 | LMNA (0.73) | LMNARECQLTYMSSCN2AL3MBTL1 | |
| SCHEMBL28960739 | 0.77 | CA12 (0.64) | LMNARECQLSCN2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3941883-A | Aromatic dicarboxamides as anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |