Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733725 | 0.87 | TBXA2R (0.39) | CTSBADRB1KDM4EALDH1A1KMT2A | |
| SCHEMBL11727609 | 0.87 | LTA4H (0.38) | ADRB1KMT2ATBXA2RPTGER1PTGFR | |
| SCHEMBL11727274 | 0.85 | TBXA2R (0.38) | ADRB1TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11725298 | 0.85 | CYP1A2 (0.45) | CASRALDH1A1KMT2ATBXA2RPTGER1 | |
| SCHEMBL11726209 | 0.82 | KDM4E (0.44) | CASRKDM4EALDH1A1KMT2ATBXA2R | |
| SCHEMBL11731623 | 0.82 | TBXA2R (0.39) | ADRB1KDM4ETBXA2RPTGER1PTGFR | |
| SCHEMBL11731322 | 0.82 | ADRB2 (0.45) | ADRB1KMT2ATBXA2RPTGER1PTGFR | |
| SCHEMBL11732616 | 0.82 | GRM2 (0.33) | GRM2CASRTBXA2RPTGER1PTGFR | |
| SCHEMBL11734063 | 0.81 | TBXA2R (0.40) | ADRB1KDM4EALDH1A1KMT2ATBXA2R | |
| SCHEMBL11733959 | 0.81 | MAPK1 (0.41) | ADRB1KDM4EALDH1A1TBXA2RPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |