Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730097 | 0.90 | TBXA2R (0.51) | LMNATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11735701 | 0.90 | ADRB2 (0.41) | ALDH1A1 | |
| SCHEMBL11725291 | 0.90 | TBXAS1 (0.43) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11726046 | 0.87 | FAAH (0.40) | LTA4H | |
| SCHEMBL11728048 | 0.87 | TBXA2R (0.40) | LMNATBXA2RPLA2G4BMEN1KMT2A | |
| SCHEMBL11733725 | 0.86 | TBXA2R (0.39) | LMNATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11731240 | 0.86 | ALDH1A1 (0.43) | LMNATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11727609 | 0.86 | LTA4H (0.38) | LMNATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11730072 | 0.85 | LMNA (0.42) | LMNATBXA2RALDH1A1LTA4HFABP4 | |
| SCHEMBL11850224 | 0.83 | PTGFR (0.57) | TBXA2RPTGER1PTGFRPTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |