Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310573 | 0.88 | DGAT1 (0.46) | PTPRCSMN1; SMN2HPGDNMUR2NPC1 | |
| SCHEMBL14520998 | 0.88 | DGAT1 (0.46) | PTPRCSMN1; SMN2HPGDNMUR2NPC1 | |
| SCHEMBL29290422 | 0.84 | GABRA1 (0.42) | PTPRCGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL28833526 | 0.84 | GPR35 (0.45) | PTPRCGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL6587338 | 0.84 | GABRA1 (0.42) | PTPRCGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL1357074 | 0.84 | HPGD (0.47) | PTPRCSMN1; SMN2HPGDNMUR2MEN1 | |
| SCHEMBL30949638 | 0.84 | GPR35 (0.45) | PTPRCGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL29279869 | 0.84 | PTPRC (0.46) | PTPRCGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL28399793 | 0.82 | MAPK1 (0.41) | PTPRCGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL30838813 | 0.82 | ALDH1A1 (0.48) | PTPRCGABRA1GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053639-A | 2-(2,2' OR 2,2'-FLUORO OR DIFLUORO-4-BIPHENYLYL)PROPAN-1-OL; ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | THE BOOTS COMPANY LIMITED (EN) | 1977-10-11 | — | — | US | disclosed |