Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732811 | 0.90 | MMP13 (0.43) | KMT2AMMP13SRC | |
| SCHEMBL11734875 | 0.84 | PGK1 (0.45) | KMT2ANPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL11732835 | 0.83 | MMP13 (0.43) | KMT2AMMP13TSHRALDH1A1SRC | |
| Hydrochloric Acid SCHEMBL11732858 | 0.80 | SRC (0.48) | KMT2AMMP13TSHRALDH1A1GAA | |
| SCHEMBL11552437 | 0.79 | SRC (0.53) | KMT2AMMP13TSHRALDH1A1GAA | |
| SCHEMBL11734775 | 0.79 | SRC (0.53) | KMT2AMMP13TSHRALDH1A1GAA | |
| SCHEMBL11737713 | 0.79 | KMT2A (0.46) | KMT2ABRD4NPC1RECQLRAB9A | |
| SCHEMBL11735105 | 0.78 | NPC1 (0.47) | KMT2ANPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL11727542 | 0.78 | MMP13 (0.50) | KMT2AMMP13NPC1TSHRAPOBEC3A | |
| SCHEMBL11551636 | 0.77 | SRC (0.56) | KMT2ABRD4TSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011324-A | Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents | PFIZER INC. (US) | 1977-03-08 | — | — | US | disclosed |